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Showing posts from April, 2018

PATHOPHYSIOLOGY OF ADDICTION-THE REAL REASON BEHIND ADDICTION

         NEUROCHEMISTRY/PATHOPHYSIOLOGY OF ADDICTION         Hello and welcome to my blog yet again. Today, we will talk about the pathophysiology of addiction.         The human body is based on the pleasure principle. It finds opportunity to find happiness wherever it can, and tries to minimize pains. This was first stated by Sigmund freud. This sense of pleasure is chiefly experienced due to the release of a special chemical in the brain, (called neurotransmitter),which is DOPAMINE. DOPAMINE is a neurotransmitter, which helps a person to experience happiness, motivation, satisfaction, satiety, sexual gratification, arousal etc. hence, a person feels these emotions in presence of this neurochemical. SEROTONIN is another neurotransmitter which also is responsible for happiness. But it seems to have slight inhibitory action of dopamine. Moreover, serotonin is also responsible for cal...

GOUT

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                  GOUT Gout or gouty arthritis/podagra is an metabolically mediated for of inflammatory arthritis which are characterized by deposition of uric acid crystals in between the joints leading to recurrent attacks of red, swollen and tender joint. The commonest joints affected by this form of inflammations are the ball of the great toe, small joints of the fingers( meta tarso phalangeal joint), also involvement of heel, wrists, knee is also not uncommon.   Classification of gouty arthritis 1.               Primary gout. 2.               Secondary gout . 1.               Primary gout: Whenever there seems no specific cause behind production of this metabolic issue, we address the person as suffering from a primary ...

THE KNEE JOINT AND ITS COMMON DISEASE.

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THE KNEE JOINT THE ANATOMY OF THE KNEE JOINT THE KNEE JOINT IS THE LARGEST JOINT IN THE HUMAN BODY.IT IS FORMED BY THREE PARTS: 1) THE LOWER END OF THE FEMUR.              2) THE UPPER END OF TIBIA .                3 )THE PATELLA. THUS, IT IS A COMPOUND JOINT. I.E, A JOINT, WHICH IS FORMED BY UNION OF MORE THAN ONE SINGLE JOINT. HERE TWO COMPONENTS MAKE UP THIS JOINT. 1)    TIBIO-FEMORAL (UPPER END OF TIBIA AND LOWER END OF FEMUR) & 2) PATELLO-FEMORAL PART (A SURFACE END OF PATELLA AND LOWER END OF FEMUR). BASICALLY, THE KNEE JOINT IS A MODIFIED TYPE OF HINGE JOINT . HINGE JOINT IS A TYPE OF JOINT WHICH PERMITS MOVEMENT IN ONE DIRECTION ONLY, i.e FLEXION AND EXTENSION, JUST LIKE A HINGE OF A DOOR WHICH PERMITS ONLY OPENING AND CLOSING MOVEMENTS OF THE DOOR. OTHER NAME FOR SUCH A JOINT IS GINGLYMUS JOINT. HOWEVER, KNEE BEING A MODIFIED COMPOUND JOI...